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Syringe-Closure-Wrap: Multifunctional Label Protects Prefilled Syringes

At Pharmapack in Paris at the beginning of February 2023, Schreiner MediPharm successfully presented its innovative security label for syringes. Syringe-Closure-Wrap met with strong interest by trade show visitors. The multifunctional label for prefilled syringes provides clear first-opening indication enabling the detection of tampering and counterfeiting attempts, or previously used products. Syringe-Closure-Wrap is unique in that it protects the integrity of the syringe and, due to its special design, offers the option of adding further protective functions and features.

Prefilled syringes require special security solutions to reliably protect both the active ingredients and the syringe. Syringe-Closure-Wrap features an innovative design: The label wraps around the entire cap and syringe barrel like a kind of second skin. This film wrap is sealed at the top, thus securing the integrity of the syringe until the injection is performed. Opening the label activates a first-opening indication feature. Special security die-cuts result in a partial destruction of the label and prevent reclosing it unnoticeably. An initially covert warning message can be integrated as an additional security feature. 

For healthcare staff, use of the label is easy, intuitive, and safe. Whether the label has been opened before can be detected immediately. For even higher product and counterfeiting protection, overt, covert, or digital authentication features can be added.  In addition, an RFID chip can be integrated for smart applications. The larger label area offers scope for customized branding and written information. Moreover, Syringe-Closure-Wrap enables numerous optional functionalities that can be adapted to the specific use case and material of the syringe—whether glass or COC—such as UV and light protection, migration barrier, or other barrier functions.  

Syringe-Closure-Wrap can be applied to the syringe in conventional dispensing processes in pharmaceutical manufacturing operations. The security label is sealed using an ultrasonic welding process without heat and thus suitable also for syringes containing sensitive active ingredients. In addition, the solution is adaptable to a wide range of syringes, using either staked-in needles or Luer-Lock.

Because, due to its special design, the label wraps around both the syringe barrel and the cap, it protects the integrity of the prefilled syringe on unit level. As a result, it is possible to either replace a blister pack or to remove it for storage purposes. This saves space during storage and transportation while conserving resources and benefiting the environment.